Especially for critical analytical applicationsEvery batch is carefully testedPre-treated bottles ensure the purity and long shelf life of solventsEach batch is shipped with a certificate of analysis
Romil Chemicals Ltd’s ultrapure solvents and acids are manufactured in a strictly controlled environment, and each batch is shipped with a certificate of analysis. Manufacturing the solvents at a single location ensures high traceability and consistency between batches, which is crucial when analyses must meet strict requirements.
The sensitivity of laboratory analysis has improved enormously in recent years. Modern LC-MS and GC systems are capable of measuring compounds at concentrations that, until recently, were practically impossible to detect. As the equipment itself is often no longer the main limiting factor in analysis, attention must increasingly shift to the entire analytical chain: sample preparation, materials and, in particular, the purity of the solvents used.
Background contamination and solvent quality can have a significant impact, particularly in trace and ultra-trace level determinations, whether the method in question is LC-MS, GC or, for example, PFAS analysis. Ultrapure solvents have been developed specifically for such demanding applications, where low background levels, consistency and analytical reliability are critical.
Romil’s ultra-pure solvents are suitable for a wide range of applications; the most common uses are listed below. You can find more detailed information on the Romil website via this link.
Liquid chromatography coupled with mass spectrometry (LC-MS) is a highly sensitive technique that requires extremely pure solvents. ROMIL‑UpS™ ultra lc products are manufactured to meet the strict requirements of these methods.
Unlike traditional HPLC, UHPLC combines particles smaller than 2 microns with shorter-length columns in high-pressure instrumentation, enabling improved resolution and efficiency in chromatographic separation. Although the resulting lower flow rates and shorter run times require less solvent, solvent purity requirements have increased. ROMIL‑UpS™ ultra LC solvents are ideally suited for this purpose.
Gas chromatography-mass spectrometry (GC-MS) requires volatile organic solvents such as dichloromethane, hexane, methanol, acetonitrile, and ethyl acetate. ROMIL‑UpS™ ultra gc versions of these solvents are carefully distilled in glass to ensure maximum purity and have been tested for use in GC-MS, GC-ECD, and GC-FID applications.
The combination of gas chromatography and ICP-MS enables the simultaneous determination of multiple elements. This combined technique is particularly well-suited for the analysis of various metals, such as lead, mercury, and zinc. Thanks to purification technology, ROMIL‑UpS™ ultra gc solvents have low metal concentrations (at the ppb level), making them ideal for use in GC-ICP-MS.
The combination of liquid chromatography and ICP-MS (LC-ICP-MS) offers many advantages in specific analytical applications. ROMIL‑UpS™ ultra LC solvents are ideally suited for this triple combination technique, as their underlying ionic impurities have been controlled to low ppb levels.
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