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NanoSight NS300

Data on size, concentration and polydispersity in minutesUser-friendly NTA softwareEasy setup of SOPsFluorescence detection

Nanosight NS300 is a system for NTA, Nanoparticle Tracking Analysis, which can characterise particles of 10 nm – 1,000 nm in solutions. Each particle is analysed individually, but simultaneously. This yields high-resolution analysis of particle size and concentration.

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Features

Technical specifications

NanoSight NS3000 allows easy analysis of the size distribution and concentration of nanoparticles and even fluorescent markers. The fully software-controlled filter wheel means automated analysis of fluorescent markers can be performed, while walk-away NTA measurements for multiple samples can be performed when used with the Sample Assistant accessory.

Measure over 1000 particles in just 60 seconds
Particle-by-particle analysis for high resolution size and concentration
Visual validation of results as the only system on the market
User-friendly software with easy setup of SOPs for routine use
Minimal sample preparation
On board temperature control
Choice of laser wavelengths
Add up to 5 additional filters in a motorized wheel for flexible fluorescence detection capability
Complies with Industry Standards ISO 19430:2016 and ASTM E 2834:2012
NanoSight NS300 uses the Nanoparticle Tracking Analysis (NTA) technology. By capturing the light scattered from particles undergoing Brownian motion, NTA provides particle-by-particle, high resolution particle size data, along with concentration measurements for colloidal suspensions or solutions of nanoparticles. A laser is directed through the sample chamber, which makes the particles in suspension scatter light. They can be easily visualised using a 20x magnifying microscope with a camera attached. The camera operates at 30 frames per second (fps), capturing a video of particles in Brownian motion. The software tracks many particles individually and, using the Stokes-Einstein equation, calculates their hydrodynamic diameters. The measurement is controlled via Standard Operating Procedures which are set with a user-friendly software interface.

Specifications

Wavelength	405nm (violet), 488nm (blue), 532nm (green) or 642nm (red).
Temperature control range	5°C below ambient to 50°C.
Stage	Fixed
Focus	Computer controlled motorized focus
Camera	sCMOS
Fluorescence	Motorized filter wheel with choice of up to 5 filters
Dimensions (W, D, H)	400mm x 250mm x 400mm.
Particle size	10nm – 1,000nm* ● Sample and system configuration dependent
Concentration range	106 … 109 particles/ml.
Power	100V – 240V

Accessories

NanoSight Sample Assistant

Up to 96 samples
2 ml deep well plates
Walk-away overnight measurements
Integrated cleaning protocol
Smart method development tools

You can find the manufacturer’s presentation on the product via this link

Syringe pump

A syringe pump is recommended for all measurements to ensure results with high statistical accuracy. The NTA software automatically compensates for flow in the sample so only the Brownian motion of the particles is used for size data.